CAS号：20788-07-2
|
英文名称：Resorantel
分子式
C13H10BrNO3
分子量
308
EINECS号
244-040-9
MDL
MFCD00864511
Smiles
InChIKey
N-(4-溴苯基)-2,6-二羟基苯甲酰胺化学百科
基本信息
| 中文名称 | 雷琐太尔 |
| 英文名称 | Resorantel |
| CAS号 | 20788-07-2 |
| 分子式 | C13H10BrNO3 |
| 分子量 | 308.13 |
| EINECS号 | 244-040-9 |
物化性质
| 熔点 | 229-230°; mp 183-186° (LeMaire) |
| 沸点 | 391.1±42.0 °C(Predicted) |
| 密度 | 1.699±0.06 g/cm3(Predicted) |
| 溶解度 | DMSO：250 mg/mL（811.35 mM；需要超声） |
| 形态 | 固体 |
| 酸度系数(pKa) | 7.62±0.35(Predicted) |
| 颜色 | 白色至米白色 |
安全信息
生产及用途
Resorantel是一种安全的抗绦虫药，对莫尼茨绦虫和Thysaniezia spp.十分有效，对Paramphistomum spp.有一定效力。
Resorantel (65 mg/kg, a single oral dose) possesses efficacy against paramphistomiasis in naturally infected sheep.
| Animal Model: | Five flocks of sheep in different villages of Haryana. |
| Dosage: | 65 mg/kg. |
| Administration: | A single oral dose. |
| Result: | None of the treated sheep died of enteric paramphistomiasis. The clinical signs disappeared within 2 to 3 days of the treatment and their appetite and general condition improved. No ill effects of the drug were noticed. Of the untreated sheep, 35 % died with a range of 24-52 % in the different flocks. Many of the other untreated sheep continued to exhibit clinical signs of paramphistomiasis. |
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