CAS号：3368-04-5
|
英文名称：4-Methylumbelliferyl phosphate
分子式
C10H9O6P
分子量
256
EINECS号
222-137-7
MDL
MFCD00016969
Smiles
InChIKey
4-甲基伞形酮酰磷酸酯化学百科
基本信息
| 中文名称 | 4-甲基伞形酮磷酸酯 |
| 英文名称 | 4-METHYLUMBELLIFERYL PHOSPHATE |
| CAS号 | 3368-04-5 |
| 分子式 | C10H9O6P |
| 分子量 | 256.15 |
| EINECS号 | 222-137-7 |
物化性质
| 熔点 | 215-218 °C |
| 沸点 | 511.4±60.0 °C(Predicted) |
| 密度 | 1.583±0.06 g/cm3(Predicted) |
| 溶解度 | DMF：10mg/mL； DMSO：20mg/mL； PBS（pH 7.2）：5 mg/mL |
| 形态 | 液体 |
| 酸度系数(pKa) | 1.65±0.10(Predicted) |
| 颜色 | 白色至类白色 |
| PH值 | pH (5g/l, 25℃) : 1.5～2.3 |
| 水溶解性 | Soluble in water |
| BRN | 1687229 |
安全信息
| 危险品标志 | Xn |
| 危险类别码 | 20/22 |
| 安全说明 | 36-24/25 |
| 危险品运输编号 | UN 1760 8/PG 2 |
| WGK Germany | 3 |
| TSCA | Yes |
| 海关编码 | 29199000 |
生产及用途
4-Methylumbelliferyl phosphate (4-MUP) 是一种碱性磷酸酶的荧光底物。
4-Methylumbelliferyl phosphate monoester previously described as one of a series of 4-methylumbelliferone conjugates is later found to be the PlP2-pyrophosphate diester and is not hydrolysed by serum phosphomonoesterases . 4-Methylumbelliferyl phosphate has a significant advantage over currently available substrates in that its useful concentration range extends to about 0.1 μM.
If the concentration of 4-Methylumbelliferyl phosphate is held constant and the pH is varied, the activity of the enzyme passes through a maximum.
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