Robinetin (3,3',4',5',7-Pentahydroxyflavone) 是一种天然黄酮,具有显着的“两种颜色”固有荧光特性,具有抗真菌、抗病毒、抗菌、抗突变和抗氧化活性。Robinetin 还可以抑制脂质过氧化和蛋白质糖基化。
Robinetin (0.1-10 μM; 1 h) inhibits HIV integrase cleavage and integration in a dose-dependent manner.
Robinetin inhibits the DNA synthesis in
Proteus vulgaris
, and the RNA synthesis in S.
aureus
.
Robinetin (100-200 or 25 μM; 1 or 72 h) inhibits egg yolk phosphatidylcholine (EYPC) membrane lipid peroxidation and hemoglobin A (HbA) glycosylation with high efficiency.
Robinetin exhibits photo-induced excited-state intramolecular proton transfer resulting in ‘two color’ (in ‘blue-violet’ and ‘yellow-green’ regions) fluorescence characteristic of flavonols, the relative contributions between the two colors being strongly modulated by the local environment of the fluorophore.